OSTEOARTHRITIS cHRONIC PAIN
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Chronic pain is a condition that affects dogs and cats and persists over time. As pets age, it is common for them to experience discomfort that should not be ignored as it could be a sign of Osteoarthritis (OA). 80% of the cats above 8yr old, and 90% of dogs above 9yr old, develop OA.
What is OA? Osteoarthritis is a common chronic condition characterized by the degeneration of joint cartilage, inflammation, and the formation of bony growths within the joints. It causes chronic pain, inflammation and stiffness in the joints, which can limit mobility and significantly impact the quality of life of pets. Pets usually develop the disease between 8 and 13 years old. This is considered a late age of diagnosis and is due to a lack of early recognition of signs of pain. Awareness and early detection can significantly improve the quality of life for pets. |
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Treating chronic pain in pets can be a complex and multifaceted process that requires a comprehensive approach. Part of the treatment requires active participation and compliance from pet owners. This includes administering medications correctly, following prescribed treatment plans, providing a suitable environment for the pet's needs, and engaging in recommended exercises or physical therapy sessions.
The development of new therapeutic approaches for treating chronic pain in companion animals is essential to provide more effective, personalized, and safer pain management options. It can significantly improve the well-being and quality of life of pets living with chronic pain and enhance our understanding of pain management in veterinary medicine as a whole.
The development of new therapeutic approaches for treating chronic pain in companion animals is essential to provide more effective, personalized, and safer pain management options. It can significantly improve the well-being and quality of life of pets living with chronic pain and enhance our understanding of pain management in veterinary medicine as a whole.
Canine atopic dermatitis
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Skin allergies are the most common health issue for dogs. Atopic dermatitis (AD) is a common skin disease in dogs.
Canine AD is a multifactorial disease process. It’s a genetically predisposed inflammatory and pruritic allergic skin disease often associated with a production of immunoglobulin (Ig) E against environmental allergens.The prevalence of AD in the dog is approximately 10–15%. Although the pathogenesis is not completely understood, there is evidence for genetic abnormalities, an altered immune system with cutaneous inflammation and a skin barrier defect. The most common symptoms associated with atopic dermatitis are scratching, itching, foul odor, loss of hair, scaly skin, etc. The breeds found to be most susceptible to this canine atopic dermatitis are Golden Retriever, German Shepherd, Labrador, and Pug. |
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FELINE ATOPIC SKIN SYNDROME
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Feline atopic skin syndrome (FASS) is an inflammatory and pruritic skin syndrome of cats manifested by a spectrum of reaction patterns and represents one of the most prevalent skin diseases among cats (20%).
The age of onset is variable but generally is 5 years. The signs may be seasonal or nonseasonal. Purebred cats may have a higher risk than domestic shorthaired cats. As in dogs, pruritic cats may have several clinical presentations (eg, miliary dermatitis, symmetric alopecia, eosinophilic granuloma complex, head and neck pruritus) that are consistent with a diagnosis of FASS but that must be differentiated from other diseases with similar clinical signs. |
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Management for feline atopy is life-long and usually involves various treatments and lifestyle changes or adjustments for the patient as well as pet owners. Depending on severity of the disease, patient and owner compliance as well as overall patient health, an individualized treatment plan is usually designed.
At Xeptiva, we have designed and produced a novel therapy to target the inflammation that underlies FASS in cats. Proof-of-concept clinical studies have shown that our technology (Xep04) is a safe, well tolerated, and effective strategy to tackle this hard to manage condition.
At Xeptiva, we have designed and produced a novel therapy to target the inflammation that underlies FASS in cats. Proof-of-concept clinical studies have shown that our technology (Xep04) is a safe, well tolerated, and effective strategy to tackle this hard to manage condition.
Dog AGING AND SENESCENCE
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Increasing the life expectancy of dogs could mean that people get to spend more time with their beloved companions, which could enhance their overall health, well-being and quality of life.
Xeptiva’s technology was designed to therapeutically prevent the accumulation of senescent cells in dogs. |
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