Pipeline / Xep04 · Cat · Atopic dermatitis

Atopic dermatitis in cats

A long-acting immunother­apy adapted to cats, tar­get­ing the neu­ro­genic inflam­ma­tion behind chronic itch and skin inflam­ma­tion.

ProgramXep04
SpeciesCat
IndicationAtopic dermatitis
StagePreclinical studies
The disease

Why it matters

Feline atopic skin syn­drome is a chronic, relaps­ing pru­ritic disease that presents as self-induced hair loss, miliary der­mati­tis, eosinophilic lesions or intense itching of the head and neck. Long-term control relies on cor­ti­cos­teroids or immuno­sup­pres­sants, which are dif­fi­cult to sustain in cats over years.

Target and mechanism

What the vaccine does

In cats, as in dogs, chronic itch is sus­tained by a loop between sensory nerves, mast cells and inflam­ma­tory medi­a­tors. Xep04 applies the plat­form to that loop in feline skin, with an immuno­gen adapted to the cat.

How the platform works →
Evidence

Preclinical studies

  • This program is cur­rently in pre­clin­i­cal studies.
Partnering

Interested in this program?

Pro­to­cols, study reports and the reg­u­la­tory package are avail­able to qual­i­fied part­ners under con­fi­den­tial­ity.